The Tank Francaise yellow gold model eventually sold for £9,766 after 46 bids, breaking the record for the charity’s biggest online auction sale.
Cartier watches have been sported by celebrities including Jake Gyllenhaal, Angelina Jolie and Michelle Obama, as well as DianaPrincess of Wales.
Cama Villiers, Enterprise Customer Success Manager at BHF’s online shopping partner, Shopiago, said: “When you consider the average value of an item donated to a charity shop is less than £5, finding a Cartier watch is like striking gold and winning Lottery at the same time.
“Anyone who was a generous donor can rest assured that their donation will go a long way toward fighting heart disease.”
In recent years BHF has sold a 7in vinyl demo of The Beatles’ Love Me Do for £9,400 and a second-hand Mercedes Benz E320 for £7,502.
The charity’s eBay site currently lists several pieces from designer brands including Gucci and Burberry.
Richard Pallier, Head of Online Retail at BHF, said: “As the largest charity in the UK supporting research into heart and circulatory disease, every donation makes a big difference to the British Heart Foundation.
“It is only through extremely generous donations from the public that we can continue to do this important work.”